NIH awarded Dr. Teresa Woodruff funding to support her study that utilizes the development of a 3-D human tissue model. “Tissue chips” are engineered to model disease and test drug efficacy prior to clinical trials. Dr. Woodruff’s study focuses on Polycystic Ovary Syndrome (PCOS), a highly prevalent human health crisis for women in their reproductive years.
This project team has created a next-generation technology that can be used in the general- or high-throughput tissue culture lab and will support human and mouse tissues (ovaries, fallopian tubes, uterus, cervix, adipose, liver and pancreas) under the influence of androgen. Project staff will use this model to test drugs that target androgen production as well as existing insulin-sensitizing drugs and a new class of drugs that is under development for PCOS by the team’s pharmaceutical partner.
Read more about the award here.